CHARLES R. DREW UNIVERSITYOF MEDICINE AND SCIENCE10th Drug Abuse Research ionResearchCDU Diversity-promoting Institutions Drug Abuse Research Development Program(DIDARP)Friday, August 7, 20158:30 am – 4:30 pmCharles R. Drew University of Medicine and ScienceKeck Lecture Hall1731 E. 120th Street, Los Angeles, CA 90059Information: please contact Dr. Friedman at 310-668-5197 or [email protected] byUCLA Integrated Substance Abuse Programs/ Pacific Southwest Addiction Technology Transfer CenterUCLA CTSI (Catalyst award)CDU AXISAgenda7:30 - 8:30 amREGISTRATION/PRE-CONFERENCE EVALUATION AND BREAKFAST8:30- 8:45 amWelcome and background on Diversity-Institutions Drug Abuse Research Program(DIDARP) at CDUTheodore Friedman, MD, PhD*DIDARP Program DirectorCharles R. Drew University of Medicine and [email protected] PowerPointCE process and evaluationsMaria CastroUCLA Integrated Substance Abuse ProgramsPacific Southwest Addiction Technology Transfer [email protected]

CME process and evaluationsJeonathan RodriguezCharles R. Drew University of Medicine and [email protected]:45- 8:55 amUniversity WelcomeAngela L. Minniefield, MPAVice President of Advancement, Strategic Development & External AffairsCharles R. Drew University of Medicine and [email protected] VideoKEYNOTE SPEAKER8:55-9:55 am Imaging brain chemistry in diseases of addiction, (CME event )Joanna Fowler, PhDSenior Chemist, emeritusBrookhaven National [email protected] Video PowerPointPOLICY RESEARCH SUBSTANCE ABUSE9:55-10:05 amIncreasing the Legal Age to Access Tobacco Product to 21: An overviewMelitta Johnson, MHA Post-baccalaureate studentCharles R. Drew [email protected] Video PowerPoint10:05-10:30 amIncreasing the Legal Age to Access Tobacco Product to 21: A Legislator’s ViewpointEd Hernandez, O.D.California State Senator (SD-22)[email protected] Video10:30-10:40 amMORNING BREAK10:40-11:00 amPublic Health Efforts to Decrease Smoking in CaliforniaTonya Gorham Gallow, MSWProgram DirectorTobacco Control and Prevention [email protected] Video PowerPointCynthia A.K. Song Mayeda, RN, PHN, BSNPublic Health NurseTobacco Control and Prevention Program2

[email protected] Video PowerPointSUBSTANCE ABUSE: CLINICAL STUDIES11:00-11:20 amScreening and Brief Intervention and Referral for Treatment: An Evidence-Based Approachto Alcohol Problem PreventionShahrzad Bazargan, PhDProfessor, Charles R. Drew [email protected] Video PowerPoint11:20-11:40 amLosing Your License to Drink: A new approach to reducing problem alcohol useGreg Midgette, PhDAssociate Policy Researcher, [email protected] Video PowerPoint11:40-12:00 pmGenetic and environmental determinants of drug useEmily Hartwell Doctoral student, Clinical Psychology, [email protected] Video PowerPointTOP STUDENT/TRAINEE ORAL PRESENTATIONS12:00-12:10 pmEffects of Alcohol on U.S. Adolescent Sleep Patterns: A Systematic ReviewNancy Carballo MSIV David Geffen School of Medicine at UCLACharles R. Drew University of Medicine & [email protected] Video PowerPoint12:10-12:20 pmNicotine stimulates muscle de novo lipogenesis in mice but when combined with a high-fatdiet it also causes intramyocellular lipid accumulation and mitochondrial abnormalitiesDesean L. Lee *Division of Endocrinology, Department of Internal Medicine,Charles R. Drew University of Medicine and [email protected] Video PowerPoint12:20-1:15 pmLUNCH BREAK AND MEET WITH DRS FOWLER AND FRANCES ANDPOSTER VIEWINGExacerbation of coke-induced, sugar coke-induced and diet coke-induced hepatic steatosisand skeletal muscle abnormalities by nicotine in obese miceRasheed Ivey, MS *Charles R. Drew University/DGSOM at UCLA MEPM.D. Candidate, MS I3

[email protected] Effects of Smoking Cessation: A Literature ReviewKindred Harris *DGSOM at UCLAM.D. Candidate, MS [email protected]:15- 1:20 pmPRESIDENTIALWELCOMEDavid M. Carlisle, MD, PhDPresident and CEOCharles R. Drew University of Medicine and [email protected] VideoTOP STUDENT/TRAINEE ORAL PRESENTATIONS1:20-1:30 pmChronic nicotine exposure during adolescence alters the rewarding properties ofthe cannabinoid agonist CP 55,940 in young adult male rats.Andrea D Hardin California State University, San [email protected] Video PowerPoint1:30-1:40 pmNicotine plus a high-fat diet triggers cardiomyocyte apoptosis in male mice by inhibitingAMP-activated protein kinase independent of fibroblast growth factor 21Mark Falz* Division of Endocrinology, Department of Internal Medicine,Charles R. Drew University of Medicine and [email protected] Video PowerPointAfternoon Session CLINICAL STUDIES1:40-1:55 pmPrescription Drug Abuse Research – DIDARP at ETSU (via videoconference)Robert Pack, PhD, MPHProfessor of Community and Behavioral HealthAssociate Dean for Academic Affairs,East Tennessee State University College of Public [email protected] Video PowerPoint1:55 -2:10 pmAffect Regulation and Smoking in WomenRaina Pang, Ph.D.Assistant Professor of Research, Department of Preventive MedicineUniversity of Southern California Keck School of [email protected] Video PowerPoint4

Afternoon Session BASIC SCIENCE2:10 -2:40 pmDrugs of abuse and brain developmentFrances M. Leslie, PhDProfessor, Pharmacology, School of MedicineJoint Appointment, Anatomy & Neurobiology, School of MedicineDean, Graduate DivisionUniversity of California, [email protected] Video PowerPoint2:40-2:55 pmNeuroimmune regulation of the mesolimbic dopamine system duringmorphine withdrawalAnna Taylor, BSc, PhD Postdoctoral FellowSemel Institute for Neuroscience and Human BehaviorUniversity of California, Los [email protected] Video PowerPoint2:55 -3:15 pmThe role of alpha2-containing nAChRs in learning, memory and addictionShahrdad Lotfipour, PhDPrincipal Investigator, David Geffen School of Medicine, [email protected] Requested not to post3:15-3:25 pm AFTERNOON BREAK3:25-3:40 pmNicotine and diabetes related genes/signaling moleculesArbi Nazarian, PhDAssociate ProfessorDepartment of PharmacologyWestern Universi[email protected] Video PowerPoint3:40-3:55 pmNicotine Plus Coke, Sugar Coke and Diet coke on body weight, food intake and hepatic andmuscle steatosisCarl Sims *Charles R. Drew University of Medicine and [email protected] Video PowerPoint3:55-4:10 pmInsight into how opioids affect brain cellsYulong Chen, PhDVisiting Assistant ResearcherHatos Center for NeuropharmacologySemel Institute for Neuroscience and Human BehaviorUCLA David Geffen School of [email protected]

Biography Requested not to Post4:10-4:25 pm4:25-4:30 pmNociceptin receptor (NOP) as a potential target for the development ofmedications to treat drug addictionKabirullah Lutfy, PhD*Professor, Department of Pharmaceutical SciencesCollege of PharmacyWestern University of Health SciencesDivision of EndocrinologyCharles R. Drew University of Medicine and [email protected] PowerPointCLOSING REMARKSPRESENTATION OF PRIZE FOR TOP TRAINEE PRESENTATIONAND POSTCONFERENCE EVALUATIONSTheodore Friedman, MD, PhD4:30 pmADJOURN*Funded by CDU DIDARP Eligible for top trainee award This specific lecture is a 1.0 AMA PRA Category 1 CreditTM certified CME event, affiliated with Drug AbuseResearch Day*(this lecture is the only CME offered within the agenda)Upon completion Joanna Fowler, Ph.D. session, participants will be able to:1. Describe PET technology2. Recognize the brain dopamine system and the response of the dopamine system to drugs ofabuse vs natural reinforces like food3. Identify the pharmacokinetics of cocaine in the human brain and the relationship to the ‘high’.4. Describe dopamine D2 receptor availability in the human brain in addicted individuals.5. Identify orbital frontal cortex metabolism in addicted individuals6. Describe non-nicotine effects of tobacco smoke exposure on the human brain.7. Summarize the effects of addiction on public healthPhysician Continuing Medical EducationAccreditation Statement: Charles R. Drew University is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.Physician Credit Designation: Charles R. Drew University designates this live activity for a maximum of 1.0 AMA PRA Category 1 CreditTM Physicians should claim only the creditcommensurate with the extent of their participation in the activity.For information about the accreditation of this program, please contact Charles R. Drew University at 323.563.9349 or [email protected] to Receive Credit: In order to receive credit for this activity, the participant must submit a completed Evaluation/Request for Credit Form to the CME Office. A Statement ofCredit will be issued only upon receipt of a Completed Activity Evaluation/Request for Credit Form. Statements of Credit will be emailed to you on a quarterly basis.Non-Physician Certificates:Non-physicians who successfully complete the activity will receive a Certificate of Participation. A Certificate of Participation will be issued only upon receipt of a completed ActivityEvaluation/Request for Credit Form. Certificates of Participation will be emailed to you on a quarterly basis.Fee Information: There is no fee for this educational activity.Disclosure of Conflicts of Interest: Charles R. Drew University requires instructors, planners, managers and other individuals and their spouses/life partners who are in a position tocontrol the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest arethoroughly vetted by Charles R. Drew University for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patientcare recommendations.Americans with Disabilities Act: Event staff will be gladly assist you with any special needs. Please contact Jeonathan Rodriguez prior to the live event at 323.563.9349 [email protected]

1:40-1:55 pm Prescription Drug Abuse Research – DIDARP at ETSU (via videoconference) Robert Pack, PhD, MPH Professor of Community and Behavioral Health Associate Dean for Academic Affairs, East Tennessee State University College of Public Health. PACKR@