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SOUTHERN UNIVERSITY AND A&M COLLEGE BATON ROUGE, LOUISIANAPhD in EnvironmentalToxicology

SOUTHERN UNIVERSITY AND A&M COLLEGE BATON ROUGE, LOUISIANADean: Dr. Patrick CarriereLacy, FredPhD - Electrical EngineeringHoward University, Washington, DCPhD in Environmental Toxicology(PhD/ENTX)Martinez-Ceballos, EduardoPhD - Cell and Molecular BiologyTulane University, New Orleans, LADepartment of Environmental ToxicologyMedicherla, SatyanarayanaPhD - Physiology and PharmacologyAndhra University/AMC, Waltair, IndiaCollege of Sciences and EngineeringSanjay Batra, PhDChairP. O. Box 9264Baton Rouge, LA 70813 Fisher Hall – Room 108Phone: 225-771-3200Fax: 225-771-5350Program Coordinator: Doris T. PattersonPhone: 225-771-3846Fax: 225-771-5350E-mail: [email protected], WesleyPhD - BiochemistryUniversity of Maryland, Baltimore, MDUppu, RaoPhD - BiochemistryOsmania University/NIN, Hyderabad, IndiaBatra, SanjayPhD - BiochemistryKanupur University/CDRI, Lucknow, IndiaMurthy, SubramanyamPhD - BiochemistryOsmania University/NIN, Hyderabad, IndiaAdjunct ProfessorsBabu, BassaPhD – BiochemistryUniversity of Delhi/VPCI, New Delhi, IndiaMensah, PatrickPhD – Engineering ScienceLouisiana State UniversityOnu, ChukwuPhD - Civil and Environmental EngineeringWest Virginia University, Morgantown, WVQi, YadongPhD - Urban ForestryStephen F. Austin State University, Nacogdoches, TXRaghavamenon, AchuthanPhD - BiochemistryMahatma Gandhi University, Kottayam, IndiaSamkutty, PushpaPhD - Dairy MicrobiologyLouisiana State University, Baton Rouge, LAStubblefield, MichaelPhD -Engineering ScienceLouisiana State University, Baton Rouge, LAWashington, SamuelPhD - Analytical ChemistryLouisiana State University, Baton Rouge, LAIntroductionThe Environmental Toxicology Program offers a Doctor of Philosophydegree in environmental toxicology. There are four study options ofwhich a student could choose one to work towards the degree. This hasto be approved by the graduate committee. The study options are1. Molecular and Reproductive Toxicology and Cell BiologyBiju, VasudevanPhD – ChemistryUniversity of Kerala, Thiruvananthapuram, India2. Toxicological Effects of Priority Toxic ChemicalsClaville, MichellePhD – Organic ChemistryUniversity of Florida, Gainesville, FL4. Microbial Treatment and Detection of Hazardous Materials andEnvironment ContaminantsHines, JamesMD - Meharry Medical College, Nashville, TN JD - SouthernUniversity, Baton Rouge, LAKousoulas, KonstatinPhD - BiotechnologyFairleigh Dickinson University, Teaneck, NJ3. Chemical Detection and Evaluation of Toxicological Substances inthe EnvironmentAs of 2017, the PhD Program in Environmental Toxicology hasproduced over 20 PhD graduates. With this experience, it is possible formaking changes in the program including course listings and optionareas as described. Students will be notified of all the changes that aremade in a timely manner, and will be made available onhttp://www.subr.edu/entox.Mission Statement2 Page

SOUTHERN UNIVERSITY AND A&M COLLEGE BATON ROUGE, LOUISIANAThe faculty of the program strive hard to train eligible individuals toconduct basic and applied research on (i) the potential adverse effectsof chemicals and complex mixtures of environmental contaminants onbiological systems and environment, (ii) to conduct research on themolecular mechanisms of chemically induced toxicity, (iii) tocommunicate the concepts and findings of toxicological research andevaluations, and (iv) to serve as an information resource ontoxicological matters to the state and the general public. The overallgoal is to advance the science of environmental toxicology and itsrelevance to the well- being of human, animal, and plant life.GRADUATE DEGREES OFFEREDPhD in Environmental ToxicologyADMISSION REQUIREMENTS An earned BS or MS degree from an accredited university in theareas of toxicology, biology, chemistry, or toxicology-relatedsubject as considered appropriate by the EnvironmentalToxicology Graduate Committee. A graduate grade point average (GPA) of 3.0/4.0 and anundergraduate GPA of 3.0/4.0 (exceptions will be made wheredeemed necessary). Undergraduate or graduate course credits of at least threesemesterhours from an accredited university in each of thefollowing: cell biology, genetics, biochemistry, and organicchemistry. Students who have not completed these prerequisitecourses may be admitted to the program on a conditional basis butwill not receive full admission until completion of thesecourses.A Graduate Record Examination score of 1000 (verbal andquantitative; old scale) or 290 (new scale). Students withexceptional GPAs who do not meet the minimum GRErequirement may be considered on an individual basis.than the beginning of the second year in residence. Based on thecommittee’s recommendation, the minimum requirements may bemodified to better prepare the student towards graduation. To remain ingood standing, each student must maintain a minimum GPA of NT-A limited number of assistantships are available for full-time studentswith regular admission and who enroll for minimum of 9 credit hours inboth Fall and Spring semesters. Further, a student receiving financialassistance is required to work in the laboratory of a designated facultyfor a minimum 20 hours/week. Initial award and continuation will bebased on academic performance and the recommendation of theGraduate Student Advisory Committee. Where funds become limiting,GPA and research productivity will be used determine the allocation.Graduate assistants dropping to less than 9 credit hours in Fall andSpring semesters or less than 6 credit hours in summer shall have theirassistantships revoked. Students who fail to qualify and subsequentlyimprove will be required to wait for one semester before applying forreconsideration.Since the PhD program is a desegregation program mandatingdiversity, special consideration shall be given to students coming fromminorities for the award of assistantships, tuition waivers and tuitionscholarships.General Tuition Waiver/ScholarshipsStudents who are enrolled full-time but do not have assistantship shallbe considered for tuition scholarship subject to1.Availability of funds2.Have a full-time load of 9 or more credit hours till the end of thesemester. A 600-word essay on the student’s career goals and interest in thetoxicology program.Any student who is employed full time elsewhere will not be eligible forreceiving financial support. Three letters of reference with at least two from former instructors.GRADUATE ADVISORY COMMITTEE Recommendation by the Graduate Admission Committee ofthe program.Each student with the help of the major advisor and the Chairmanshould have an advisory committee before the beginning of the secondyear. The advisory committee should consist of no fewer than fourmembers of the graduate faculty. At least two members, including theProgram Leader will be from the Environmental Toxicology Programrecommending the degree, and at least one member drawn from adifferent educational discipline.GRADUATION REQUIREMENTSFor students entering the program with a MS degree, the minimumcoursework requirement is 36 hours, typically comprising 21 hours ofcore courses, 9 hours of toxicology electives, and 6 hours of generalelectives, exclusive of the thesis, doctoral dissertation and research.Students entering the program with a BS degree are required tocomplete an additional 18 hours of MS-level foundation courses inbiology, chemistry, or toxicology.Upon completion of the core courses, students must pass the GraduateComprehensive Exam (GCE) to become a candidate for the PhDdegree. After passing the GCE, students may register for dissertationresearch credit hours.Students who earn more than two grades of C or below shall beautomatically dismissed from the program. In consultation with theadvisory committee, each student must develop a plan of study no later3 PageCOURSE OF STUDYCore Courses (twenty-two hours are required) ***ENTX 700 Bioethics . 3 creditsENTX 710 Environmental Toxicology Seminar .1 credit*ENTX 721 Principles of Environmental Toxicology I . 3 creditsENTX 722 Principles of Environmental Toxicology II. 3 creditsENTX 723 Advanced Biochemistry I. 3 creditsENTX 725 Biochemical and Molecular Toxicology. 3 creditsENTX 731 Animal Physiology. 3 credits

SOUTHERN UNIVERSITY AND A&M COLLEGE BATON ROUGE, LOUISIANAENTX 737 Biochemical Method. 3 credits*** must be taken once, may be repeated up to four times** 3 credits are required may be repeated up to 6 credits*** B or better is required for all the core coursesToxicology Electives (nine hours are required)ENTX 724 Advanced Biochemistry II . 3 creditsENTX 732 Aquatic Toxicology . 3 creditsENTX 733 Cell Physiology . 3 creditsENTX 736 Special Topics in Toxicology. 3 credits(Credit, 1 hour). This course must be taken once, but may berepeated for a maximum of 4 hours. Requirements include reports bystudents, resident faculty and distinguished visiting faculty on topics ofcurrent interest in Environmental Toxicology.ENTX 721-722 PRINCIPLES OF ENVIRONMENTALTOXICOLOGY I & II (Credit, 3 hours each). Introduction to thebasic principles of environmental toxicology; applications of theseprinciples in industrial and other job related environments; regulatoryperspectives; spills; anthropogenic pollution problems; human riskmanagement; overview of classes of toxic agents, routes of exposure,target tissues (human and other mammalian species); testing andscreening agents for genotoxic activities; molecular genetic approachesto environmental biomonitoring.ENTX 757 Bioinformatics . 3 creditsENTX 723 ADVANCED BIOCHEMISTRY I (Credit, 3 hours). Anadvanced biochemistry course concerned with major metabolicpathways and their control. The metabolism of carbohydrates, proteins,lipids, and nucleic acids is discussed. Bioenergetics is also featuredand details the production and utilization of energy by the cell. Othertopics include metabolic diseases with emphasis on molecular control,response to toxins, and adaptation of cells to pollutants.General Electives* (six hours are required)ENTX 725 BIOCHEMICAL AND MOLECULAR TOXICOLOGYENTX 740 Environmental Microbiology . 3 creditsCHEM 560 Toxic Substances, Effects, and Controls . 3 creditsPPOL 750Environmental Regulations and Law . 3 creditsENTX 750 Organ System Toxicology . 3 creditsBIOL 506Biostatistics: Experimental Design and Analysis (orSMED739 Applied Statistics). 3 creditsENTX 744 Risk Assessment . 3 creditsENTX 753 Recent Advances in Virology. 3 creditsENTX 755 Molecular Immunology . 3 credits*These courses could be selected from existing courses in otherPhD programs, other master’s programs, including Chemistry,Biology, Nursing, Urban Forestry, or Public Policy.Research Courses***ENTX 799 Environmental ToxicologyResearch Practicum . 3-6 CreditsENTX 800 Dissertation Research . 3-9 Credits***may be repeated for a minimum of fifteen hours each.A MINIMUM TOTAL OF THIRTY-SIX HOURS ARE REQUIREDTO COMPLETE THE CURRICULUM(Credit, 3 hours). The effects of chemicals onbiochemical pathways,target organelles (e.g.,mitochondria, lysosomes), and specific enzymes are thecentral theme of the course. Selected topics include,phase I and II xenobiotic metabolism, generation ofreactive intermediates of chemicals, genotoxicology andprinciples of chemical carcinogenesis.ENTX 731 ANIMAL PHYSIOLOGY (Credit, 3 hours). Acomprehensive and integrated course designed to cover the principlesand fundamental concepts associated with the functional activities andmechanisms of action involved with the coordination and maintenanceof homeostasis, bioenergetics, biocatalysis and metabolic processes.Clinical and toxicological relationships will also be covered.ENTX 737 BIOCHEMICAL METHODS (Credit, 3 hours). Mustbe repeated for a maximum of 4 hours degree credit. This is a laboratoryrotation course where students are exposed to current methodology inthe environmental and biochemical sciences. This course will involvetheoretical and practical applications of quantitative and qualitativemeasurement in biological systems. Students enrolled in this course willdo nine-week rotations in selected research laboratories and give anoral presentation on methods learned during the rotation.COURSE DESCRIPTIONSToxicology ElectivesCore CoursesENTX 724 ADVANCED BIOCHEMISTRY II (Credit, 3 hours).ENTX 700 BIOETHICS (Credit, 3 hours). Topics include thebioethical considerations and concerns that confront the conduct ofresearch and its perceptions by the general public. Special attention isgiven to the ethics of environmentally related research, journalism,human experimentation, genetic research, professional roleresponsibility, and conflicts of interests. The course also coversInstitutional Review Board policies as well as Institutional Animal Careand Use Committees as mandated by the National Institutes of Health.The course will be taught from a multi-disciplinary approach to provideopportunities for the full participation of students.ENTX 710 ENVIRONMENTAL TOXICOLOGY SEMINAR4 PageThis course features a study of the effects ofenvironmental contaminants on aquatic and marineorganisms. The relationships between impact onindividual organisms, populations, communities andecosystems, relative effects of chemicals on larvae andembryo development, biomarkers of pollutant exposurefor early-warning detection of deleterious effects ofchemicals, bioaccumulation and bioavailability of effluents,sedimentand other particulate adsorption models,ecological risk assessment for aquatic toxicants olism, adaptation and toxicity.

SOUTHERN UNIVERSITY AND A&M COLLEGE BATON ROUGE, LOUISIANAstudent’s advisory committee. General electives are designed to enrichthe individual student’s graduate degree program.ENTX 732 AQUATIC TOXICOLOGY (Credit, 3 hours). Thiscourse features a study of the effects of environmental contaminants onaquatic and marine organisms. The relationships between impact onindividual organisms, populations, communities and ecosystems, relativeeffects of chemicals on larvae and embryo development, biomarkers ofpollutant exposure for early-warning detection of deleterious effects ofchemicals, bioaccumulation and bioavailability of effluents, sedimentand other particulate adsorption models, ecological risk assessment foraquatic toxicants and comparative biochemical mechanisms, includingmetabolism, adaptation and toxicity.ENTX 726 ADVANCED BIOSTATISTICS (Credit, 3 hours).This course is designed to acquaint advanced toxicology students withresearch designs for biological experimentations. Emphasis is onparametric and nonparametric statistical analysis and their applicationsto more advanced experiments.ENTX 733 CELL PHYSIOLOGY (Credit, 3 hours). A study of thefundamental cellular functions with emphasis on molecular andbiochemical principles, enzyme catalysis, metabolic pathways, the flowof information and energy, and energy transformation and mobilization.Methods of identification for hazardous chemicals arediscussed, as well as the possible adverse health effectsassociated with these chemicals. The course also focuseson chemical dose-response in humans, chemicalexposure assessment in various environmental conditions.ENTX 744 RISK ASSESSMENT (Credit, 3 hours). This coursefocuses on the risk of hazardous chemicals to plants and animals., and the characterization of risk to a given population.ENTX 736 SPECIAL TOPICS IN TOXICOLOGY (Credit, 1-3hours). May be repeated for a maximum of 9 hours degree credit. Thiscourse will cover current topics pertaining to Environmental Toxicology.Issues relating to method development and application, toxin andanalysis, disease prevention, environmental issues and newenvironmental law are possible topics.ENTX 740 ENVIRONMENTAL MICROBIOLOGY (Credit, 3hours). This course will involve an advanced study of the practices ofbiodegradation and bioremediation with emphasis on microbial ecology.Specific topics include the basic concepts ofENTX 741 AIR POLLUTANTS AND HEALTH (Credit, 3 hours).The science and technology of air pollution and its control, effectsof air pollutants on plant and animal life and on inanimate objectsand materials, and methods of detecting and measuring airpollutants and their effects on the environmentENTX 750 ORGAN SYSTEMS TOXICOLOGY (Credit, 3hours). The course features topics related to the effects of chemicaltoxicants and toxins on the various major organ systems of mammalianand other vertebrate models. Topics include systematic study of thetoxicity of chemicals on hepatic, neural, endocrine, renal, circulatory,and immune systems. A central theme is the nature of the organsystems and its relationship to organ-specific toxicity of chemicals.ENTX 757 Bioinformatics (Credit, 3 hours). This is anintroductory web-based course that focuses on the assessment ofBioinformatics in Environmental Toxicology. Principles, techniques, andapplications in the fields of genetic engineering, sequence alignment,substitution methods, phylogenetics, genomics, and gene recognition,are emphasized. The course also offers hands-on experience withsubject related computer programs and algorithms.General ElectivesThe listed and additional general electives that are consistent with thestudent’s program of study may be taken with the approval of the5 PageENTX 753 RECENT ADVANCES IN VIROLOGY (Credit, 3 hours).This course offers an advanced analysis of the biology andpathogenic effects of animal viruses. Recent advances anddiscoveries in the field of virology are discussed. The latest methodsof virus detection and treatment are also discussed.ENTX 755 MOLECULAR IMMUNOLOGY (Credit, 3 hours). Thiscourse focuses on cell-mediated immune responses. Specialemphasis is given to the formation of the immune system at themolecular level, as well as the antigen-antibody relationship, themolecular structure of immunoglobulins, autoimmunity, and immunedeficiency diseases and treatment.ResearchENTX 799 TOXICOLOGY RESEARCH PRACTICUM (Credit, 3-6hours). This course provides the opportunity for students to conductbasic and applied research under the direction of an EnvironmentalToxicology faculty member. Students will develop questions relatedto toxicological research and conduct practical research aimed atanswering the question. Emphasis will placed on the use of “thescientific method”, making scientific observations, and recordingdata. Further, data analysis, interpretation and data presentation inthe form of abstracts, scientific papers, and research proposals willbe covered. This course is only open to students who have not yetqualified for PhD candidacy.ENTX 800 DISSERTATION RESEARCH (Credit, 3-9 hours). Eachstudent is required to conduct research that is aimed at producing adissertation. The student and supervising faculty will choose aresearch topic related to toxicological research and conduct theresearch in a cooperative manner. This course is only open tostudents who have qualified for PhD candidacy. Each student mustperform dissertation research in a timely manner and submit thedissertation

PhD - Electrical Engineering . Howard University,Washington,DC Martinez-Ceballos, Eduardo . PhD - Cell and Molecular Biology . Since the PhD program is a desegregation program mandating . PhD programs, other master’s programs, including Chemistry