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SyringePump.comModel: NE-1000Multi-Phaser NE-1000 Series of Programmable Syringe PumpsFirmware Version: V3.923Infusion S YOUR APPLICATION?” WARNINGNOT FOR CLINICALUSE ON HUMANSPublication #1200-01Firmware Version: V3.92304/06/16
New Era Pump Systems Inc.www.SyringePump.comModel NE-1000 Multi-Phaser Quick Start InstructionsAssumes that the pump was not previous programmed with a multiple Phase Pumping Program. Plug in the pump.Press the power switch to turn on power.Press any key to stop the display from blinking.Setup Pumping ParametersTo Change Numbers: Use the up-arrow keys to increment individual digits. To set/clear the decimal point: Simultaneously press the 2 up-arrow keys under the 2 digits next to the decimalpoint position. Alternatively, press and hold the left-most up-arrow key for at least 1 second. When the digitincrements from 9 to 0, the decimal point will begin to shift. Release the key when the decimal point is correct. Press any non-arrow key, or wait 2 seconds, to enter the new setting. The display will blink when a new value isentered and stored in memory.Set the Syringe Inside Diameter: Momentarily press the ‘Diameter’ key. Set the inside diameter of the syringe in millimeters (mm).Set the Pumping Rate. Momentarily press the ‘Rate’ key. To change the pumping rate units: Momentarily press the ‘Rate’ key again. The display will show: Press any up-arrow key to select the next available rate units while the units LEDs are blinking. Press any non-arrow key, or wait 2 seconds, to set the rate units.Set the pumping rate. If the pumping rate is out of range, the display will show:Set the Volume to be Dispensed or Continuous Pumping Momentarily press the ‘Volume’ key. When the display showsthe display to 0. For continuous pumping: Set the volume to 0. For a Volume to be Dispensed: Set the volume. The default units are set according to the syringe diameter., the pump is set for continuous pumping. Pressing any up arrow key will changeSet the Pumping Direction When the ‘Withdraw’ LED is lit, the pump is set for withdrawing. When not lit, the pump is set for infusing. Use the‘’ key to change the pumping direction.Load the Syringe Press in the white drive-nut button to move the pusher block. Insert the syringe plunger in the pusher block slot. Insert the syringe barrel flange in the flange brackets with the syringe barrel holder on the syringe. Tighten the flangebrackets onto the syringe flange. Tighten the pusher block screw.Prime / Purge: Press and hold the ‘Start/Stop’ key for one second. Release to stop.Start the Pump: Press and release the ‘Start/Stop’ key to start or stop the pump.When Pumping The pumping rate can be changed. With continuous pumping, the pumping direction can be changed.PUMP RESET: Press and hold the right-most up-arrow key while turning on power to the pump.Publication #1200-01i04/06/16
New Era Pump Systems Inc.www.SyringePump.comModel NE-1000 Multi-Phaser Table of Contents1.GENERAL INFORMATION . 11.11.21.31.42.WARNINGS ! AND CAUTIONS ! . 1DISCLAIMER . 1WARRANTY . 2PACKING LIST . 2OVERVIEW . 22.1GLOSSARY OF TERMINOLOGY AND CONCEPTS . 33.SETUP . 54.LOADING SYRINGES . 55.GUIDE ROD COLLAR CLAMP (MODEL NE-1000 ONLY) . 56.USER INTERFACE. 66.1 ENTERING VALUES . 66.2 LCD DISPLAY . 66.3 LEDS . 6. 76.4 ARROW AND DECIMAL POINT KEYS . 76.4.1DECIMAL POINT . 76.5 ‘DIAMETER’ AND ‘SETUP’ KEY. 76.6 ‘RATE’ AND ‘PROGRAM PHASE #’ KEY . 86.6.1PUMPING RATE UNITS . 86.6.2PROGRAM ENTRY MODE . 86.7 ‘VOLUME’ AND ‘PROGRAM FUNCTION’ KEY . 86.7.1DISABLING “VOLUME TO BE DISPENSED” . 86.7.2CLEARING “VOLUME DISPENSED” . 96.7.3PROGRAM ENTRY MODE . 96.8 PUMPING DIRECTION KEY . 96.8.1STICKY DIRECTION . 96.9 ‘START’/’STOP’ KEY . 96.10‘PROGRAM PHASE #’ (NUMBER) KEY. 106.11‘PROGRAM FUNCTION’ KEY . 106.11.1 PROGRAM PHASE FUNCTION PARAMETER . 106.12‘SETUP’ KEY . 106.13SPECIAL POWER-UP FUNCTIONS . 106.13.1 FIRMWARE VERSION DISPLAY . 106.13.2 RESET PUMPING PROGRAM . 116.13.3 DEFAULT PROGRAM PRE-LOAD . 116.13.4 PROGRAM ENTRY MODE LOCKOUT. 116.14ERROR AND ALARM MESSAGES . 116.15STATUS MESSAGES . 127.OPERATION. 127.1 SYRINGE INSIDE DIAMETER. 127.1.1DEFAULT VOLUME UNITS. 127.1.2CHANGING VOLUME UNITS . 137.2 START/STOP TRIGGERS . 137.3 OPERATING THE PUMP . 137.4 PURGING. 13Publication #1200-01ii04/06/16
New Era Pump Systems Inc.7.57.67.77.88.www.SyringePump.comModel NE-1000 Multi-Phaser CHANGING THE PUMPING RATE AND DIRECTION WHILE PUMPING . 13VOLUME DISPENSED. 13RESUMING WHEN PAUSED . 14PUMP STALLED . 14SETUP CONFIGURATION . 148.18.28.38.48.58.68.78.88.99.POWER FAILURE MODE . 15LOW NOISE MODE . 15AUDIBLE ALARM ENABLE . 15TTL I/O OPERATIONAL TRIGGER DEFAULT CONFIGURATION . 16TTL I/O DIRECTIONAL CONTROL INPUT CONFIGURATION . 16PUMP MOTOR OPERATING TTL OUTPUT CONFIGURATION . 17KEYPAD LOCKOUT . 17KEYPAD AND NOTIFICATION BEEP ENABLE . 17RS-232 PUMP NETWORK CONFIGURATION . 17PUMPING PROGRAM. 189.1 HOW TO ENTER PUMPING PROGRAMS . 189.1.1PUMPING PROGRAM PHASE NUMBER . 199.2 PUMPING PROGRAM EDIT FUNCTIONS . 199.3 PROGRAM FUNCTION DESCRIPTIONS . 209.3.1‘RATE’: RATE FUNCTION . 209.3.2‘FILL’: FILL FUNCTION . 209.3.3‘INCR’: INCREMENT RATE FUNCTION. 209.3.4‘DECR’: DECREMENT RATE FUNCTION . 219.3.5‘STOP’: STOP PUMPING OPERATION AND END THE PROGRAM. 219.3.6‘JP:NN’: JUMP TO PHASE . 219.3.7'PR:IN': SUB-PROGRAM SELECTION INPUT. 219.3.8'PR:NN': SUB-PROGRAM START LABEL . 229.3.9‘LP:ST’: DEFINE STARTING PHASE OF LOOP. 229.3.10 ‘LP:EN’: DEFINE CONTINUOUS LOOP END . 229.3.11 ‘LP:NN’: DEFINE LOOP END AND LOOP REPETITIONS . 229.3.12 'PS:NN': PAUSE PUMPING . 229.3.13 'IF:NN': JUMP TO PHASE IF EXTERNAL TRIGGER . 239.3.14 'ET:NN': SETUP EVENT TRIGGER JUMP PHASE . 239.3.15 'ES:NN': SETUP EVENT SQUARE WAVE TRIGGER JUMP PHASE . 239.3.16 'ET:RS': EVENT RESET . 239.3.17 ‘CLR.D’: CLEAR TOTAL VOLUME DISPENSED . 239.3.18 ‘TR:AA’: OVERRIDE OPERATIONAL TRIGGER CONFIGURATION . 249.3.19 'OUT.N': SET TTL OUTPUT PIN . 249.3.20 'BEEP': BEEP . 249.4 PUMPING PROGRAM EXAMPLES. 249.4.1EXAMPLE 1: 2 STEP RATE . 249.4.2EXAMPLE 2: REPEATED DISPENSES WITH SUCK BACK . 259.4.3EXAMPLE 3: RAMPING THE FLOW RATE . 269.4.4EXAMPLE 4: COMPLEX DISPENSES WITH EXTERNAL SYNCHRONIZATION . 279.4.5EXAMPLE 5: CONTROL FROM A HIGH-LOW PRESSURE SENSOR . 289.4.6EXAMPLE 6: AUTOMATED DISPENSING WITH SYNCHRONIZATION. 299.4.7EXAMPLE 7: SUB-PROGRAMS . 309.4.8EXAMPLE 8: DISPENSING WITH COMPLEX SYNCHRONIZATION . 319.4.9EXAMPLE 9: AUTOMATIC REFILL . 3210.10.1RS-232 COMMUNICATIONS . 32CONNECTION AND NETWORKING . 32Publication #1200-01iii04/06/16
New Era Pump Systems Inc.www.SyringePump.comModel NE-1000 Multi-Phaser 10.2RS-232 PROTOCOL: . 3310.2.1 RS-232 GENERAL SYNTAX LEGEND . 3310.2.2 RS-232 PROTOCOL: BASIC MODE . 3410.2.3 RS-232 PROTOCOL: SAFE MODE . 3410.2.4 RS-232 PROTOCOL: BASIC AND SAFE MODE COMMON SYNTAX . 3510.2.5 NETWORK COMMAND BURST . 3610.3COMMAND ERRORS AND ALARMS . 3610.4RS-232 COMMAND SET. 3610.4.1 PROGRAM FUNCTION COMMANDS . 3710.4.2 PUMP OPERATIONAL COMMANDS . 3910.4.3 CONFIGURATION AND SETUP COMMANDS . 3910.4.4 GENERAL CONTROL AND STATUS COMMANDS . 4110.4.5 SYSTEM COMMANDS . 4110.5GETTING STARTED WITH RS-232 . 4211.11.111.211.312.LOGIC INTERFACE: TTL INPUT AND OUTPUT . 43TTL I/O OPERATIONAL CONTROLS . 44TTL I/O CONTROL FROM THE PUMPING PROGRAM . 45TTL I/O CONTROL FROM RS-232 . 45APPENDIX . 4612.1RS-232 COMMAND SUMMARY . 4612.2RS-232 PUMP NETWORK CONNECTOR WIRING . 4712.3ACCESSORIES . 4712.3.1 ANA-BOX . 4712.3.2 SYRINGE HEATER . 4712.3.3 RS-232 NETWORK CABLES. 4712.3.4 AUTOMATION CABLE: SPECIAL COMMUNICATIONS MODES CONTROL CABLE . 4812.3.5 VALVE CONTROLLER . 4812.3.6 FOOT SWITCH. 4812.3.7 LOCKOUT DISABLE KEY . 4812.3.8 FIRMWARE UPGRADE . 4812.4TROUBLESHOOTING AND MAINTENANCE . 4812.5SPECIFICATIONS . 4912.6CUSTOM APPLICATIONS . 4912.7SYRINGE DIAMETERS AND RATE LIMITS . 50Publication #1200-01iv04/06/16
www.SyringePump.comNew Era Pump Systems Inc.Model NE-1000 Multi-Phaser 1. General InformationThank you for purchasing the NE-1000 Multi-Phaser Programmable Syringe Pump. With the NE-1000syringe pump you will be able to perform simple infusions or implement a complex automated dispensingsystem.Please familiarize yourself with the NE-1000’s operation by reading this user's manual. For futurereference, record the serial number, located on the rear of the pump, and the date of purchase.New Era Pump Systems Inc., located in Farmingdale, NY USA, can be contacted at:Phone: (631) 249-1392 FAX: (707) 248-2089Email: [email protected] Operating Manual, and the NE-1000’s hardware, electronics and firmware are copyrighted.Copyright 1999-2014, all rights reserved.1.1 Warnings!and Cautions !!Read the user’s manual!No user serviceable parts are inside.!Disconnect power from the pump when connecting or disconnecting cables.!Do not immerse the pump in liquid!Install on a stable surface.!Keep hands and loose clothing away from the pump's moving parts.!The pump can automatically start when the Pumping Program is operating or when attached to anexternal control device.!Prevent liquids from entering openings in the rear of the pump.!Use only with the supplied power supply connected to a power source as specified on the powersupply label.!Do not push objects of any kind into the chassis openings, except for appropriate cables andconnectors.!If the pump becomes damaged, do not use unless certified safe by a qualified technician. Damageincludes, but is not excluded to, frayed cords and deterioration in performance.!!Discharge static from control cables before connecting by touching the cable to ground.Before touching the pump, discharge static by touching ground.1.2 DisclaimerNew Era Pump Systems Inc. makes no representations or warranties, expressed, statutory or implied,regarding the fitness or merchantability of this product for any particular purpose. Further, New Era PumpSystems Inc. is not liable for any damages, including but not limited to, lost profits, lost savings, or otherincidental or consequential damages arising from ownership or use of this product, or for any delay in theperformance of its obligations under the warranty due to causes beyond its control. New Era PumpSystems Inc. also reserves the right to make any improvements or modifications to the product describedin this manual at any time, without notice of these changes.New Era Pump Systems Inc. products are not designed, intended, or authorized for use in applications oras system components intended to support or sustain human life, as a clinical medical device for humans,or for any application in which the failure of the product could create a situation where personal injury ordeath may occur.All brand and product names used in this manual are the trademarks of their respective owners.Publication #1200-01104/06/16
New Era Pump Systems Inc.www.SyringePump.comModel NE-1000 Multi-Phaser 1.3 WarrantyNew Era Pump Systems Inc. warranties this product and accessories for a period of two years, parts andlabor, from the date of purchase. The repaired unit will be covered for the period of the remainder of theoriginal warranty or 90 days, whichever is greater. Return shipping charges are not included.A return authorization number must be obtained from New Era Pump Systems Inc. before returning a unitfor repair. Warranty covered repairs will not be performed without a return authorization number. At theoption of New Era Pump Systems Inc., a defective unit will be either repaired or replaced.This warranty does not cover damage by any cause including, but not limited to, any malfunction, defector failure caused by or resulting from unauthorized service or parts, improper maintenance, operationcontrary to furnished instructions, shipping or transit accidents, modifications or repair by the user, harshenvironments, misuse, neglect, abuse, accident, incorrect line voltage, fire, flood, other natural disasters,or normal wear and tear. Changes or modifications not approved by New Era Pump Systems Inc. couldvoid the warranty. Wearable parts, such as drive nuts, are not covered by the warranty.The foregoing is in lieu of all other expressed warranties and New Era Pump Systems Inc. does notassume or authorize any party to assume for it any other obligation or liability.1.4 Packing ListIncluded with the NE-1000 Multi-Phaser Programmable Syringe Pump are the following items: One of the following external power supply adapters:Input: One of: 120V AC 60 Hz, 220V AC 50 Hz, 240V AC 50 HZ,or other custom specified power supplyOutput: 12V DC @ 800 mA (or compatible regulated power supply) Hex wrench for adjustable guide rod collar (located in the tool holder on the back ofthe syringe holder). Model NE-1000 only. This Operating Manual2. OverviewThe model NE-1000 is a general purpose single syringe pump capable of infusion and withdrawal. It iscontrolled from a microcontroller based system which drives a step motor, allowing a large range ofpumping rates configured to the inside diameter of the loaded syringe. The syringe is driven from a drivescrew and drive-nut mechanism.Features: Infusion and withdrawal pumping of syringesup to 60 mL. 140 mL partially filled. Pumping rates from 0.73 µL/hr with a 1 mLsyringe to 2120 mL/hr with a 60 mL syringe. Stall detection: Automatically stops pumpwhen pumping is impeded. Infusion and withdrawal volumes separatelyaccumulated. Programmable dispense volumes. Programmable Phases allowing complexpumping applications and interaction withexternal devices. Program Sub-Programs, selectable by the user. Non-volatile memory of all operatingparameters and Pumping Program.Publication #1200-01 RS-232 bi-directional control from a computer Built-in pump network driver. Pump networksupports up to 100 pumps and other devices. Two modes of RS-232 control, Basic and Safe.Safe mode provides communication errordetection, loss of communication detection, andautomatic transmitting of alarm conditions. TTL logic I/O with firmware filtered controlinputs to eliminate glitches and ringing on thecontrol inputs. Configurable and programmable TTLoperational trigger for flexible logic control. Power Failure Mode: Restarts the PumpingProgram after a power interruption. Audible Alarm. Many more features!204/06/16
www.SyringePump.comNew Era Pump Systems Inc.Model NE-1000 Multi-Phaser 2.1 Glossary of Terminology and ConceptsWhen a device has as many features as the NE-1000, understanding its operation could be a daunting task atfirst. By understanding the key concepts and terminology used in this manual, the operation of the NE-1000will become quite intuitive. Every effort has been made to design the NE-1000 with a consistent and intuitiveuser interface.To facilitate and enhance your understanding of the NE-1000’s operation, please take the time to familiarizeyourself with the basic concepts below:45679831011122113161514Parts of the Pump1) Pusher Block10) Syringe Retainer Bracket2) End Plate11) Syringe Holder Block3) Anti-Siphon Plate Adjustment Knob12) ‘V’ Slot (on Syringe Holder Block)4) Power On/Off Switch13) Syringe Clamp5) Drive-Nut Button14) Keypad / User Interface6) Anti-Siphon Plate15) Guide Rod Collar Clamp7) Drive-Screw16) Guide Rod (2 guide rods)8) Syringe Retainer Thumbscrew (2, one on each side)9) Hex Wrench (in tool holder)Parts of a SyringePlungerFlangePlungerPublication #1200-01Barrel Flange3Barrel04/06/16
New Era Pump Systems Inc.www.SyringePump.comModel NE-1000 Multi-Phaser TerminologyMomentary Press:A quick press, less then 1 second, then release of a key on the keypad.Display Blink:A momentary blanking of the LCD display. This indicates that the new dataentered by the user is valid and has been stored.Program EntryMode:The mode where the Program Phase and Program function are selected andmodified. In this mode the ‘Program Phase #’ and the ‘Program Function’modes of the ‘Rate’ and ‘Volume’ keys are relevant.Pumping Program:The sequence of automated operations entered into the pump. This could be assimple as a single function to pump at a single infusion rate continuously.Pumping ProgramOperating:When the pump is started with the ‘Start’/’Stop’ key, or any other source, thepump begins performing the operations in the Pumping Program until thePumping Program either stops automatically or the pump is stopped when the‘Start/Stop’ key is pressed, or from any other source. While performing theoperations defined in the Pumping Program, the Pumping Program is referred toas operating.While Operating, the motor can be pumping or stopped, according to thePumping Program.Pumping ProgramStopped:The motor is stopped and the pump is not operating the Pumping Program.Pumping ProgramPaused:The Pumping Program has been stopped, but can be resumed at the point whereit was stopped.Pumping ProgramResumed:Continuing a Pumping Program that was Paused before the completion of thePumping Program. The Pumping Program continues at the point where thePumping Program was stopped.Executed:The pump has performed a single operational Phase as defined in the PumpingProgram.Program Phase:A single defined operation in the Pumping Program.Phase Number:A Program Phase’s numerical sequence location in the Pumping Program.Currently SelectedFunction:Each Pumping Program Phase instructs the pump to perform a particularoperation. Only one Program Phase is selected at any one time. This is thecurrent Phase. Each Phase is set to one function. The set function of the currentPhase is the currently selected function.Pumping RateFunction:Each Pumping Program function instructs the pump to perform a particularoperation. If the Phase’s operation instructs the NE-1000 to pump, thenassociated with that Phase is the Phases’ pumping information. When ‘ProgramEntry Mode’ is exited, the ‘Rate’, ‘Volume’, and pumping direction keys referto the currently selected Program Phase’s function. The Program functions thatare associated with pumping information are referred to as Pumping Ratefunctions.FunctionParameter:Certain functions, which do not instruct the NE-1000 to pump, requireadditional data. This additional data, displayed with the function, is thefunction’s parameter.Start Trigger:The Pumping Program may be started, or stopped, from multiple sources.These are the keypad’s ‘Start’/’Stop’ key, the TTL I/O ‘Operational Trigger’input, or from a command received through the RS-232 connection.Publication #1200-01404/06/16
New Era Pump Systems Inc.www.SyringePump.comModel NE-1000 Multi-Phaser 3. Setup Place the pump on a stable surface. Plug the round connector end of the supplied power supply adapter into the power plug located on thelower right of the pump's rear. See section 11, Logic Interface: TTL Input and Output, for a diagram ofthe rear of the pump. Plug the other end of the power supply adapter into an appropriate electrical outlet.The pump will be powered when the bottom of the power switch, located on the upper right of the rear ofthe pump, labeled ‘1’, is pressed. The red indicator on the switch is visible when the power switch is inthe ‘on’ position. After power is applied to the pump, the pump’s display will flash. Next the Pumping Program can be entered. Before the Pumping Program can be operated, the pumpneeds the measurement of the inside diameter, in millimeters, of the syringe that will be loaded. Thesyringe diameter can be entered using the keypad on the front panel of the pump. Finally, the syringe can be loaded and the pump started.4. Loading SyringesThe syringe is loaded by securing the barrel and the pusher flange as follows:1:Loosen the 2 thumbscrews on the syringe retainer bracket.2:Press in fully the white drive-nut button on the pusher block, releasing the block. Taking care not todrag the drive-nut on the drive-screw, slide the block away from the syringe holder, providing suffi
When not lit, the pump is set for infusing. Use the ' ' key to change the pumping direction. Load the Syringe Press in the white drive-nut button to move the pusher block. Insert the syringe plunger in the pusher block slot. Insert the syringe barrel flange in the flange brackets with the syringe barrel holder on the syringe.
